Research progress in anti-U1 ribonucleoprotein antibody in connective tissue diseases
10.3760/cma.j.cn112309-20231114-00134
- VernacularTitle:抗U1核糖核蛋白抗体在结缔组织病中的研究进展
- Author:
Baocheng LIU
1
;
Weizhen XIANG
;
Qingrui YANG
;
Zhenzhen MA
Author Information
1. 山东第一医科大学附属省立医院风湿免疫科,济南 250021
- Publication Type:Journal Article
- Keywords:
Connective tissue diseases;
Anti-U1RNP antibody;
Autoimmune diseases
- From:
Chinese Journal of Microbiology and Immunology
2025;45(1):72-77
- CountryChina
- Language:Chinese
-
Abstract:
Connective tissue diseases (CTDs) are autoimmune disorders primarily characterized by the involvement of multiple organs and systems. These diseases often have a hidden onset and complex progression, and are difficult to diagnose. Anti-U1 ribonucleoprotein (U1RNP) antibody is an important component of the anti-extractable nuclear antigen antibody spectrum, which has important clinical significance for the diagnosis and differential diagnosis of multiple CTDs and is related to organ involvement. This article introduces the characteristics of anti-U1RNP antibody and provides a comprehensive review of the recent research progress in anti-U1RNP antibodies in CTDs, aiming to help clinical workers better understand anti-U1RNP antibody.