The modulating effects of electrical stimulation of the right median nerve on arousal patterns in the prefrontal cortex
10.3760/cma.j.cn421666-20250321-00246
- VernacularTitle:右侧正中神经电刺激促醒模式对健康成年人前额叶皮质调控效应的功能性近红外光谱成像技术研究
- Author:
Ningqing XIE
1
;
Yu GONG
1
;
Xin ZHANG
1
;
Ying LIU
1
;
Weijing LIAO
1
Author Information
1. 武汉大学中南医院神经康复科，武汉 430071
- Publication Type:Journal Article
- Keywords:
Right median nerve;
Electrical stimulation;
Functional near-infrared spectroscopy;
Prefrontal cortex;
Oxyhemoglobin;
Deoxyhemoglobin
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2025;47(10):896-900
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore any effect of electrical stimulation of the right median nerve (RMNS) in modulating arousal patterns in the prefrontal cortex of a healthy adult.Methods:Twenty-three right-handed healthy participants received block-designed patterns of RMNS arousal. Functional near-infrared spectroscopy (fNIRS) was used to record any hemodynamic response in their prefrontal cortex. Changes in oxyhemoglobin (HbO), deoxyhemoglobin (HbR), and total hemoglobin (HbT) were analyzed by comparing the levels in stimulation blocks with resting-state periods.Results:fNIRS revealed significant activation of HbO signals in the left frontopolar area (channel 15) and the right frontopolar area (channels 37, 43 and 48) following RMNS arousal. There were significant differences in the HbR signals from the right frontopolar area (channel 41). There were, however, no significant differences in the HbT signals across all the measured channels.Conclusion:RMNS arousal enhances neurometabolic activity within the frontopolar sub-region of the prefrontal cortex in healthy adults.
