Comparative analysis of the therapeutic effects of transcranial magnetic stimulation targeting the primary motor cotice of handand the lower limb or sciatic nerve on motor dysfunction after a spinal cord injury
10.3760/cma.j.cn421666-20250111-00030
- VernacularTitle:重复经颅磁刺激靶向作用M1区不同部位或磁刺激坐骨神经治疗脊髓损伤后运动障碍的疗效对比观察
- Author:
Xin ZHANG
1
;
Yixing LU
;
Xinyu LIU
;
Tao HAN
;
Xiangbo WU
;
Chunqiu DAI
;
Hua YUAN
;
Xiaolong SUN
Author Information
1. 空军军医大学第一附属医院（西京医院）康复医学科，西安 710032
- Publication Type:Journal Article
- Keywords:
Transcranial magnetic stimulation;
Spinal cord injury;
Motor dysfunction
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2025;47(8):710-714
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the effect of repeated transcranial magnetic stimulation (rTMS) targeting the M1 hand area, the M1 lower limb area, or the sciatic nerve on the motor functioning and ability in the activities of daily living of persons after a spinal cord injury (SCI).Methods:This was a retrospective analysis of data describing 86 hospitalized SCI patients. They were divided into four groups based on where the rTMS was applied: an M1 hand area group ( n=22), an M1 lower limb area group ( n=20), a sciatic nerve group ( n=24), and a control group ( n=20) who never received rTMS. In addition to conventional medication and rehabilitation training, the M1 hand area group, the M1 lower limb area group and the sciatic nerve group received 10Hz rTMS over the named area for 4 weeks. Before and after the treatment, the Spinal Cord Independence Measure (SCIM) total scores, SCIM indoor activity (SCIM12) sub-scores, Modified Barthel Index (MBI) scores, and lower extremity motor (LEMS) scores were compared among the four groups. Results:After the treatment, the average SCIM, SCIM12, MBI, and LEMS scores had improved significantly in all four groups. The average SCIM [10.00(4.00, 24.75] and MBI scores [12.00(6.75, 31.50)] of the M1 hand area group were then significantly better than the control group′s averages [3.50(0.00, 9.50) and 7.50(1.25, 17.75)]. There was also significantly greater improvement in the average LEMS score of the M1 hand area group [2.00(0.00, 10.00)] compared with both the sciatic nerve group [0.00(0.00, 2.00)] and the control group [0.00(0.00, 1.75)].Conclusions:High-frequency rTMS stimulation of the M1 hand area significantly promotes the recovery of lower limb motor function and self-care ability after an SCI. It is more effective than stimulating the M1 lower limb area or the sciatic nerve.
