Clinical value of 68Ga-Pentixafor PET/CT in classification of subtypes of primary aldosteronism
10.3760/cma.j.cn321828-20240314-00099
- VernacularTitle:68Ga-Pentixafor PET/CT在原发性醛固酮增多症分型中的临床价值
- Author:
Na ZHANG
1
;
Yang XIE
1
;
Yue CHEN
1
Author Information
1. 西南医科大学附属医院核医学科、核医学与分子影像四川省重点实验室、西南医科大学核医学研究所，泸州 646000
- Publication Type:Journal Article
- Keywords:
Hyperaldosteronism;
Peptides, cyclic;
Receptors, CXCR4;
Gallium radioisotopes;
Positron-emission tomography;
Tomography, X-ray computed;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2025;45(3):185-188
- CountryChina
- Language:Chinese
-
Abstract:
Primary aldosteronism (PA) is one of the most common causes of secondary hypertension, and is one of the risk factors of cardiovascular and metabolic diseases. Its incidence increases with the increase of hypertension level. The early diagnosis and treatment of PA are important. The subtype classification of PA is vital but challenging, which is related to the treatment options. Although adrenal vein sampling (AVS) is currently recognized as the gold standard for subtype diagnosis of PA, it′s an invasive test that is technically challenging and expensive, which limits its clinical use. As a non-invasive imaging method, 68Ga-Pentixafor PET/CT can visualize, locate and characterize the lesions, and facilitate PA subtyping. This article reviews the research of 68Ga-Pentixafor PET/CT in the subtype diagnosis of PA.
