Research progress of label-free Raman spectroscopy in glioma surgery
10.3760/cma.j.cn321828-20241227-00449
- VernacularTitle:无标记拉曼光谱技术在脑胶质瘤术中的研究进展
- Author:
Dou LU
1
;
Lijun ZHU
;
Qingqing ZHOU
;
Qing XU
;
Guangming LU
Author Information
1. 徐州医科大学医学影像学院，徐州 221004
- Publication Type:Journal Article
- Keywords:
Glioma;
Spectrum analysis, Raman;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2025;45(11):700-704
- CountryChina
- Language:Chinese
-
Abstract:
Gliomas, with their infiltrative growth and malignant potential, present considerable therapeutic challenges. Maximal safe resection is essential for optimizing patient survival and quality of life. Despite this, existing intraoperative visualization techniques suffer from limited sensitivity and accuracy. Label-free Raman spectroscopy has emerged as a non-invasive, rapidly diagnostic, and highly accurate technique. It accurately diagnoses tumors, identifies infiltration margins, and classifies molecular subtypes, enhancing the precision of glioma surgery. This review summarizes the latest advances and applications of label-free Raman spectroscopy in glioma surgery.
