Application and value of PET imaging with molecular probes targeting TSPO in cardiovascular diseases
10.3760/cma.j.cn321828-20241220-00440
- VernacularTitle:TSPO靶向分子探针PET显像在心血管疾病中的应用价值
- Author:
Xuezhi LIN
1
;
Guojian ZHANG
Author Information
1. 内蒙古医科大学第一临床医学院，呼和浩特 010050
- Publication Type:Journal Article
- Keywords:
Cardiovascular diseases;
Receptors, GABA-A;
Positron-emission tomography;
TSPO;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2025;45(11):694-699
- CountryChina
- Language:Chinese
-
Abstract:
Molecular probes targeting the 18×10 3 translocator protein (TSPO) have the ability to identify and monitor tissue inflammation. Their application has expanded from neurological disorders to cardiovascular diseases (CVD), showing promising clinical translational potential in both diagnosis and therapeutic evaluation. This paper introduces the application and value of PET imaging using various generations of TSPO-targeted molecular probes in CVD, including atherosclerosis, acute myocardial infarction, large vessel vasculitis, and others.
