Research progress of immune checkpoint therapy in advanced thyroid cancer
10.3760/cma.j.cn321828-20241115-00400
- VernacularTitle:晚期甲状腺癌免疫检查点疗法的研究进展
- Author:
Pan CHEN
1
;
Yunzheng JIANG
;
Xiaoyang YUAN
;
Jinghui ZOU
;
Letong WANG
;
Lingwei GU
Author Information
1. 南方医科大学珠江医院核医学科,广州 510280
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Immunotherapy;
Immune checkpoint proteins;
Immune checkpoint inhibitors;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2025;45(10):632-636
- CountryChina
- Language:Chinese
-
Abstract:
Thyroid cancer (TC) is the most prevalent malignancy of the endocrine system. While most patients achieve favorable prognoses with early treatment, patients with advanced TC face a scarcity of effective therapeutic strategies. The thyroid gland is one of the most immunogenic tissues in the human body. With the deepening understanding of immune evasion mechanisms in TC and the application of immunotherapy in various solid malignancies, immune checkpoint therapy for TC has shown considerable therapeutic potential, offering new hope for patients with advanced TC. This paper focuses on summarizing the latest advancements in immune checkpoint therapy for TC, aiming to provide new directions for future research.