Application of 18F-MFBG PET/CT imaging in the diagnosis and treatment of neural crest-derived tumors
10.3760/cma.j.cn321828-20241019-00355
- VernacularTitle:18F-MFBG PET/CT显像在神经嵴源性肿瘤诊治中的应用
- Author:
Xuezhi LIN
1
;
Haibo LIU
;
Guojian ZHANG
Author Information
1. 内蒙古医科大学第一临床医学院,呼和浩特 010050
- Publication Type:Journal Article
- Keywords:
Adrenal gland neoplasms;
Fluorobenzenes;
Fluorine radioisotopes;
Positron-emission tomography;
Tomography, X-ray computed;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2025;45(9):571-576
- CountryChina
- Language:Chinese
-
Abstract:
The human norepinephrine transporter(hNET)is expressed in neural crest-derived tumors, such as neuroblastoma, pheochromocytoma, and paraganglioma. 18F-meta-fluorobenzylguanidine (MFBG) has high affinity and specificity for hNET, and has been gradually applied to PET/CT imaging in neural crest-derived tumors. The application of 18F-MFBG PET/CT imaging in the diagnosis and treatment of neural crest-derived tumors is reviewed in this article.