Clinical research progress on classic myeloproliferative neoplasms with hypertension
10.3760/cma.j.cn121090-20240811-00300
- VernacularTitle:经典型骨髓增殖性肿瘤伴高血压的临床研究进展
- Author:
Wenhao ZHANG
1
;
Gusheng TANG
1
Author Information
1. 海军军医大学第一附属医院血液病科,上海 200433
- Publication Type:Journal Article
- From:
Chinese Journal of Hematology
2025;46(6):583-587
- CountryChina
- Language:Chinese
-
Abstract:
Chronic myeloproliferative neoplasms (MPNs) are a group of acquired malignant tumors characterized by clonal proliferation of hematopoietic stem cells, among which polycythemia vera, essential thrombocythemia, and primary myelofibrosis are known as the classical Philadelphia chromosome-negative MPN. Hypertension is the most common complication in patients with MPN and has a significant effect on the clinical presentation, disease progression, treatment, and prognosis of patients with MPN. However, it may not have received sufficient attention from hematologists in clinical practice. This article reviews the epidemiology and clinical issues of patients with MPN and comorbid hypertension to assist clinicians in providing individualized treatment for these patients.