Mechanisms of electrical stimulation in the management of peripheral nerve injury: a review
10.3760/cma.j.cn501098-20250108-00019
- VernacularTitle:电刺激在周围神经损伤治疗中的作用机制研究进展
- Author:
Xing DU
1
;
Hongjiu QIN
Author Information
1. 皖南医学院第一附属医院电生理科，芜湖 241000
- Publication Type:Journal Article
- Keywords:
Electrical stimulation;
Peripheral nerves;
Muscular atrophy;
Neuropathic pain
- From:
Chinese Journal of Trauma
2025;41(7):688-693
- CountryChina
- Language:Chinese
-
Abstract:
Peripheral nerve injury can lead to sensory, motor and autonomic dysfunctions in the corresponding innervated areas, seriously affecting patients′ quality of life. Current treatments for peripheral nerve injury include surgical repair, neurotrophic drug therapy, and physical rehabilitation, but their therapeutic effect is often unsatisfactory. Nerve and muscle electrical stimulation therapy is a technique that applies pulsed electrical stimulation to peripheral nerves or muscles. Electrical stimulation can accelerate nerve regeneration, attenuate denervated muscle atrophy and alleviate neuropathic pain. Admittedly, its efficacy remains controversial due to unclear mechanisms of action and lack of standardized parameter settings. To this end, the authors reviewed the research progress on the mechanism of electrical stimulation for peripheral nerve injury, aiming to provide valuable references for subsequent basic research and clinical transformation.
