Establishment and Feasibility Study of an Intracranial Atherosclerosis Scoring System
10.3760/cma.j.issn.0254-9026.2025.04.012
- VernacularTitle:颅内动脉粥样硬化评分的建立及可行性研究
- Author:
Yange CHANG
1
;
Yan SONG
;
Xue YU
;
Juan HUANG
;
Sheng JIAO
;
Shu WU
;
Jiayuan HU
;
Tianqi HUANG
;
Yupeng SUN
;
Fusui JI
Author Information
1. 北京医院放射科 国家老年医学中心 中国医学科学院老年医学研究院，北京 100730
- Publication Type:Journal Article
- Keywords:
Intracranial Arteriosclerosis;
Brain Infarction;
Cerebral Angiography
- From:
Chinese Journal of Geriatrics
2025;44(4):477-483
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study aims to initially establish a scoring system for comprehensively reflecting the severity of intracranial atherosclerotic lesions and to explore the correlation between this score and atherosclerotic risk factors as well as stroke events.Methods:This study retrospectively analyzed patients who underwent head and neck computer tomography angiography(CTA)examinations and had head MRI examinations within one month before or after the CTA examination from January 2021 to August 2024 in Beijing Hospital.An intracranial atherosclerosis disease score(ICADS)system was constructed based on the degree and number of vascular stenosis.The relationship between ICADS and atherosclerotic risk factors was explored by grouping patients according to the quartile of ICADS.Patients were divided into acute stroke group and non-acute stroke group to compare differences in ICADS and cerebrovascular disease risk factors between the two groups, and to investigate the correlation between stroke events and ICADS.Results:There were statistically significant differences in the proportions of patients with hypertension and diabetes among different ICADS groups.Multiple linear regression analysis showed that hypertension( B=1.17, 95% CI: 0.20-2.14, P<0.05)and diabetes( B=2.75, 95% CI: 1.85-3.64, P<0.001)were risk factors for higher ICADS.The ICADS was higher in the acute stroke group than in the non-acute stroke group(9 vs.6, P<0.001), and a higher ICADS was identified as a risk factor for stroke( OR=1.10, 95% CI: 1.07-1.14, P<0.001). Conclusions:ICADS can comprehensively reflect the severity of intracranial atherosclerotic lesions and is correlated with stroke events, making it useful for clinical screening of high-risk patients for stroke.
