Association analysis of cardiometabolic index with different subtypes of hypertension in the elderly: a study based on the Chinese population
10.3760/cma.j.issn.0254-9026.2025.08.006
- VernacularTitle:心脏代谢指数与老年人群高血压病不同亚型的关联分析：一项基于中国人群的研究
- Author:
Chunwei HE
1
;
Jie PENG
;
Lin SHEN
Author Information
1. 山东大学齐鲁医院重症医学科，济南 250012
- Publication Type:Journal Article
- Keywords:
Cardiometabolic index;
Hypertension;
Subtype of hypertension
- From:
Chinese Journal of Geriatrics
2025;44(8):1040-1047
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Objective To investigate the association between cardiometabolic index(CMI)and hypertension subtypes in elderly Chinese population and provide a scientific evidence for hypertension classification and personalized intervention.Methods:A cross-sectional study was conducted, including 1 022 elderly patients(≥ 60 years old)admitted to Qilu Hospital of Shandong University from January to December 2015.Patients with secondary hypertension and severe complications were excluded.Blood pressure, waist circumference, blood lipid, and other indicators were measured through standardized procedures, Multivariate logistic regression was used to analyze the association between CMI and subtypes, and stratified analysis was conducted based on gender, smoking, age, pulse and metabolic indicators.Results:CMI was significantly higher in SDH group than in other subtypes( P<0.01). Waist circumference, body mass index and triglycerides were positively correlated with all three types of hypertensions( P<0.05). The multivariate model showed that CMI was an independent risk factor for hypertension subtypes(SDH OR=6.14, IDH OR=4.14, ISH OR=3.28, all P<0.01). Stratified analysis showed that CMI was associated with all subtypes in females( P<0.01), while in males, it was only associated with IDH and SDH.The effect of CMI was stronger in non-smokers(SDH OR=9.56, P<0.001). Hyperglycemia and different concentrations of low-density lipoprotein cholesterol levels aggravate the effect of CMI on SDH. Conclusions:CMI may be an independent risk factor for hypertension subtypes in the elderly.The differences in gender, metabolic status and smoking behavior provide a basis for precise intervention.
