Analysis of risk factors for lower extremity venous thrombosis in elderly patients with pulmonary tuberculosis
10.3760/cma.j.issn.0254-9026.2025.06.017
- VernacularTitle:老年肺结核患者下肢深静脉血栓发生的风险因素分析
- Author:
Qing YANG
1
;
Qiuyue LIU
Author Information
1. 首都医科大学附属北京胸科医院超声科，北京 101149
- Publication Type:Journal Article
- Keywords:
Tuberculosis;
Venous thrombosis;
Risk;
Factors
- From:
Chinese Journal of Geriatrics
2025;44(6):772-775
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the risk factors for deep venous thrombosis(DVT)in elderly patients with pulmonary tuberculosis.Methods:A total of 240 elderly patients(≥60 years old)with pulmonary tuberculosis, admitted to Beijing Chest Hospital from January 2020 to August 2024, were retrospectively analyzed.Based on the results of lower extremity venous ultrasound, the patients were divided into a DVT group(80 cases)and a non-DVT group(160 cases).The risk factors for DVT were analyzed using univariate and multivariate logistic regression.Results:Univariate analysis revealed that age, diabetes mellitus, chronic heart failure, prolonged bed rest, elevated D-dimer levels, decreased serum albumin, sputum positivity, and other factors were significantly more prevalent in the thrombosis group compared to the non-thrombosis group( P<0.05).Additionally, multivariate logistic regression analysis indicated that age ≥75 years( OR=2.15, 95% CI: 1.32-3.52), chronic heart failure( OR=2.90, 95% CI: 1.35-6.20), bed rest ≥7 days( OR=3.25, 95% CI: 1.75-6.05), D-dimer ≥3.0 mg/L( OR=5.05, 95% CI: 2.71-9.42), sputum positivity( OR=2.34, 95% CI: 1.28-4.29), and low albumin levels( OR=1.89, 95% CI: 1.17-3.06)were identified as risk factors for lower extremity DVT in elderly patients with pulmonary tuberculosis. Conclusions:The risk of DVT in elderly patients with pulmonary tuberculosis is closely associated with pathogen activity, abnormal coagulation function, and prolonged bed rest.The combination of D-dimer levels and sputum positivity can effectively screen for high-risk populations.Clinicians should prioritize early identification and intervention in these high-risk groups to reduce the incidence of DVT.
