Research progress of long noncoding RNA in atopic dermatitis

VernacularTitle:长链非编码RNA在特应性皮炎中的研究进展
Author: Xin LIU ¹ ; Xinying CAI
Author Information

1. 安徽医科大学第一附属医院皮肤性病科，合肥　230032
Publication Type:Journal Article
Keywords: RNA, long noncoding; Dermatitis, atopic; Skin barrier; Immune imbalance
From: Chinese Journal of Medical Genetics 2025;42(2):244-248
CountryChina
Language:Chinese
Abstract: Long noncoding RNA (lncRNA) is a type of RNA that is longer than 200 nucleotides and does not encode proteins. Atopic dermatitis (AD) is a common chronic inflammatory skin disease. Genetic susceptibility, damaged skin barrier and immune imbalance play important roles in its pathogenesis. Studies have shown that abnormal expression of lncRNA plays an important role in the development of many human diseases. In recent years, it has been found that various lncRNAs are abnormally expressed in AD patients and are involved in the development of AD. This paper reviews the research progress of lncRNAs in AD, aiming to provide more reference for the pathogenesis and treatment of AD.