Guideline for diagnosis and treatment of infection after internal fixation of closed lower limb fractures in adults (version 2025)

Bobin MI; Faqi CAO; Weixian HU; Wu ZHOU; Chenchen YAN; Hui LI; Yun SUN; Yuan XIONG; Jinmi ZHAO; Qikai HUA; Xinbao WU; Xieyuan JIANG; Dianying ZHANG; Zhongguo FU; Dankai WU; Guangyao LIU; Guodong LIU; Tengbo YU; Jinhai TAN; Xi CHEN; Fengfei LIN; Zhangyuan LIN; Dongfa LIAO; Aiguo WANG; Shiwu DONG; Gaoxing LUO; Zhao XIE; Dong SUN; Dehao FU; Yunfeng CHEN; Changqing ZHANG; Kun LIU; Deye SONG; Yongjun RUI; Fei WU; Ximing LIU; Junwen WANG; Meng ZHAO; Biao CHE; Bing HU; Chengjian HE; Guanglin WANG; Xiao CHEN; Guandong DAI; Shiyuan FANG; Wenchao SONG; Ming CHEN; Guanghua GUO; Yongqing XU; Lei YANG; Wenqian ZHANG; Kun ZHANG; Xin TANG; Hua CHEN; Weiguo XU; Shuquan GUO; Yong LIU; Xiaodong GUO; Zhewei YE; Liming XIONG; Tian XIA; Hongbin WU; Qisheng ZHOU; Mengfei LIU; Yiqiang HU; Yanjiu HAN; Hang XUE; Kangkang ZHA; Wei CHEN; Zhiyong HOU; Bin YU; Jiacan SU; Peifu TANG; Baoguo JIANG; Guohui LIU

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Guideline for diagnosis and treatment of infection after internal fixation of closed lower limb fractures in adults (version 2025)

VernacularTitle:成人闭合性下肢骨折内固定术后感染诊疗指南（2025版）
Author: Bobin MI ¹ ; Faqi CAO ; Weixian HU ; Wu ZHOU ; Chenchen YAN ; Hui LI ; Yun SUN ; Yuan XIONG ; Jinmi ZHAO ; Qikai HUA ; Xinbao WU ; Xieyuan JIANG ; Dianying ZHANG ; Zhongguo FU ; Dankai WU ; Guangyao LIU ; Guodong LIU ; Tengbo YU ; Jinhai TAN ; Xi CHEN ; Fengfei LIN ; Zhangyuan LIN ; Dongfa LIAO ; Aiguo WANG ; Shiwu DONG ; Gaoxing LUO ; Zhao XIE ; Dong SUN ; Dehao FU ; Yunfeng CHEN ; Changqing ZHANG ; Kun LIU ; Deye SONG ; Yongjun RUI ; Fei WU ; Ximing LIU ; Junwen WANG ; Meng ZHAO ; Biao CHE ; Bing HU ; Chengjian HE ; Guanglin WANG ; Xiao CHEN ; Guandong DAI ; Shiyuan FANG ; Wenchao SONG ; Ming CHEN ; Guanghua GUO ; Yongqing XU ; Lei YANG ; Wenqian ZHANG ; Kun ZHANG ; Xin TANG ; Hua CHEN ; Weiguo XU ; Shuquan GUO ; Yong LIU ; Xiaodong GUO ; Zhewei YE ; Liming XIONG ; Tian XIA ; Hongbin WU ; Qisheng ZHOU ; Mengfei LIU ; Yiqiang HU ; Yanjiu HAN ; Hang XUE ; Kangkang ZHA ; Wei CHEN ; Zhiyong HOU ; Bin YU ; Jiacan SU ; Peifu TANG ; Baoguo JIANG ; Guohui LIU
Author Information

1. 华中科技大学同济医学院附属协和医院，武汉　430022
Publication Type:Journal Article
Keywords: Bones of lower extremity; Fractures, closed; Fracture fixation, internal; Infection
From: Chinese Journal of Trauma 2025;41(5):421-432
CountryChina
Language:Chinese
Abstract: Postoperative infection of internal fixation of closed fractures the lower limbs in adults represents a devastating complication, characterized by diagnostic challenges, prolonged treatment duration and high disability rates. Current management of these infections faces multiple challenges, such as difficulties in early accurate diagnosis, and various controversies about the treatment plan, leading to poor overall diagnosis and treatment results. To address these issues, based on evidence-based medicine and principles with emphasis on scientific rigor, clinical applicability and innovation, the Trauma Branch of the Chinese Medical Association, Orthopedic Branch of the Chinese Medical Doctor Association, Orthopedics Branch of the Chinese Medical Association, and Trauma Orthopedics and Polytrauma Group of the Resuscitation and Emergency Committee of the Chinese Medical Doctor Association have collaboratively organized a panel of relevant experts to develop the Guideline for diagnosis and treatment of infection after internal fixation of closed lower limb fractures in adults ( version 2025). The guideline proposed 10 recommendations, aiming to provide a foundation for standardized diagnosis and treatment of postoperative infection in adults with closed lower limb fractures.