Study on Distribution Law of TCM Syndrome Elements in Obesity with Metabolic Associated Fatty Liver Disease
10.19879/j.cnki.1005-5304.202505596
- VernacularTitle:肥胖症伴代谢相关脂肪性肝病中医证素分布规律研究
- Author:
Zhaoyi CHEN
1
;
Jinkun WANG
;
Jun ZHOU
;
Shengxian LI
;
Minting LUO
;
Zhongqi YUAN
;
Lu LIU
;
Qiuyu XIA
;
Bin LI
Author Information
1. 首都医科大学附属北京中医医院,针灸神经调控北京市重点实验室,数智针灸北京市重点实验室,北京 100010
- Publication Type:Journal Article
- Keywords:
obesity;
metabolic associated fatty liver disease;
factor analysis;
clustering analysis;
syndrome elements
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(12):154-159
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the characteristics of TCM syndromes in patients with obesity with metabolic associated fatty liver disease(MAFLD).Methods TCM Symptom Collection Form was developed to collect the clinical symptoms of obesity patients who attended the Department of Acupuncture and Moxibustion of Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,from July to December of 2024.Factor analysis and clustering analysis were used to explore the distribution law of different syndrome elements and TCM syndromes.Results A total of 309 obese patients(221 with MAFLD)were included,with 20 symptoms with a frequency of≥5%.Factor analysis suggested that there was a significant difference between the two groups in the pathogenic syndrome elements of qi stagnation,yin deficiency,qi deficiency,hyperactivity of yang,yang deficiency,dampness,dynamic wind,and the locus of disease syndrome elements of the spleen and the heart spirit(P<0.05).Clustering analysis showed that the syndrome types of patients with MAFLD were mainly the syndrome of liver and stomach stagnation and heat,the syndrome of spleen deficiency and stomach heat,and the syndrome of spleen and kidney deficiency;the syndrome types of patients without MAFLD were mainly spleen-stomach qi stagnation,gastrointestinal excess-heat,spleen-deficiency-dampness obstruction,and spleen-kidney deficiency.Conclusion Patients of obesity with MAFLD are more likely to have the co-existence of the pathogenesis of damp-heat obstruction and spleen-kidney deficiency.
