Trends of Incidence and Age of Onset for Ovarian Cancer in Cancer Registration Areas of Jiangsu Province from 2009 to 2019
10.11735/j.issn.1004-0242.2025.11.A003
- VernacularTitle:2009-2019年江苏省肿瘤登记地区卵巢癌发病趋势及年龄变化特征分析
- Author:
Guanrong WANG
1
;
Renqiang HAN
1
;
Weigang MIAO
1
;
Bijia JIANG
1
;
Ran TAO
1
;
Jinyi ZHOU
1
Author Information
1. 江苏省疾病预防控制中心,江苏南京 210009
- Publication Type:Journal Article
- Keywords:
ovarian cancer;
incidence rate;
trend analysis;
average annual percentage change;
Jiangsu
- From:
China Cancer
2025;34(11):847-853
- CountryChina
- Language:Chinese
-
Abstract:
[Purpose]To analyze the trends of incidence and age of onset of ovarian cancer in can-cer registration areas of Jiangsu Province from 2009 to 2019.[Methods]Based on data reported by 16 cancer registries in Jiangsu Province,the average annual change percentage(AAPC)of ovarian cancer crude rate(CR),age-standardized incidence rate by Chinese standard population(ASIRC),proportion of cases in people over 60 years old of age were calculated by Joinpoint software.The linear regression model was used to calculate the trend of the mean age of onset and the standardi-zed average age of onset.The change trend of ovarian cancer incidence rate among people born in different periods using the birth cohort from 1929 to 2019.[Results]The CR(AAPC=4.18％,P＜0.001)and ASIRC(AAPC=2.11％,P=0.010)of ovarian cancer from 2009 to 2019 showed a significant increasing trend.The CR of ovarian cancer in urban areas was higher than that in rural areas,however,the CR in rural areas showed a significant upward trend(AAPC=4.85％,P＜0.05),while it was not significantly changed in urban areas.The incidence of ovarian cancer first increased and then decreased with age,and peaked at the age group of 60～69 years old.From 2009 to 2019,the incidence trend of different age groups varied,but the age group over 50 years showed an up-ward trend,and the upward trend became more significantly as age increased.From 2009 to 2019,the crude mean age of onset and the standardized mean age of onset in Jiangsu Province showed a significant upward trend,with an average annual increase of 0.572 years and 0.380 years,respectively(P＜0.05).The average age of onset in both urban and rural areas showed a sig-nificant upward trend,and the annual increase in urban areas was higher than that in rural areas.However,there was no significant change in rural areas after adjusting the population composi-tion.Compared with 2009,the standardized age proportion of ovarian cancer in Jiangsu Province in 2019 showed a backward trend.Standardized proportion of ovarian cancer among people over 60 years old showed a significant upward trend(AAPC=2.78％,P=0.010).[Conclusion]From 2009 to 2019,the incidence rate of ovarian cancer in Jiangsu Province showed an upward trend.Compared with urban areas,the increase in rural areas was more pronounced.The average age of onset of ovarian cancer has shifted later with the increasing cases in older individuals.
