Carotid plaque thickness combined with TyG index predicts early neurological deterioration in hypertension patients with acute cerebral infarction
10.3969/j.issn.1009-0126.2025.11.021
- VernacularTitle:颈动脉斑块厚度联合三酰甘油葡萄糖指数预测脑梗死患者早期神经功能恶化
- Author:
Yingfeng JIANG
1
;
Hui SHEN
;
Shaojin WANG
Author Information
1. 海口市人民医院超声医学科,海口 570000
- Publication Type:Journal Article
- Keywords:
carotid stenosis;
glycemic index;
hypertension;
cerebral infarction;
early neurological deterioration
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(11):1539-1542
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the predictive value of maximum thickness of carotid plaque combined with triglyceride glucose(TyG)index for early neurological deterioration(END)in elderly patients with hypertension combined with acute cerebral infarction(ACI).Methods A prospective study was conducted on 120 elderly hypertensive patients with concomitant ACI admitted in our hospital between October 2022 and October 2024.According to the occurrence of END or not,they were divided into an END group(48 cases)and a non-END group(72 cases).The clinical data and ultrasound parameters were collected in all patients.Multivariate logistic regression analysis was used to determine the factors influencing the occurrence of END.ROC curve was plotted to assess the predictive value of the maximum thickness of the carotid plaque and the TyG index for END.Results The END group exhibited significantly higher SBP at admission,higher low-density lipoprotein cholesterol,TyG index and thicker maximum thickness of carotid plaque than the non-END group(P＜0.05,P＜0.01).TyG index and maximum thickness of carotid plaque were influencing factors for END occurrence in elderly hypertension patients with ACI.The AUC value of TyG index,carotid plaque maximum thickness and their combination for predicting the occurrence of END was 0.801,0.774 and 0.911,respectively,with the combination showing better predictive efficiency(P＜0.01).Conclusion TyG index and maximum thickness of carotid plaque are influencing factors for END in elderly patients with hypertension combined with ACI,and their combination has better predictive value for END in the patients.
