Predictive value of three stroke scale models on prognosis of acute cerebral infarction after intravenous thrombolytic therapy
10.3969/j.issn.1009-0126.2025.11.005
- VernacularTitle:三种脑卒中量表模型对急性脑梗死患者静脉溶栓治疗预后的预测价值
- Author:
Shanshan LIU
1
;
Liang ZHONG
;
Xiaoxuan HAN
;
Lulu JIANG
Author Information
1. 山东省胜利油田中心医院急诊科,山东东营 257000
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
thrombolytic therapy;
forecasting;
prognosis;
scale assessment
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(11):1463-1466
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the predictive value of Alberta stroke program early CT score(ASPECTS),acute stroke registry and analysis of Lausanne(ASTRAL)and totaled health risks in vascular events(THRIVE)for prognosis of intravenous thrombolysis in elderly patients with acute cerebral infarction(ACI).Methods A total of 118 elderly ACI patients receiving intravenous thrombolytic therapy in Department of Emergency Medicine of Shengli Oilfield Central Hospital from January 2021 to September 2024 were prospectively recruited.According to the score of Modified Rankin scale(mRS)at 3 months after treatment,the patients were divided into good prognosis group(73 cases)and poor prognosis group(45 cases).The scores of ASPECTS,ASTRAL and THRIVE models were compared between the two groups.ROC curve was plotted to evaluate the predictive efficiency of the three models for 3-month prognosis,and the area under the curve(AUC)was calculated.Results The poor prognosis group had significantly higher ASTRAL score and THRIVE score but obviously lower ASPECTS score when compared to the good prognosis group(P＜0.01).ROC curve analysis revealed that the AUC value of ASPECTS,ASTRAL and THRIVE models for prognosis evaluation was 0.731,0.935 and 0.799,respectively(P＜0.01),with excellent goodness of fit.Conclusion All the three models can effectively predict the prognosis of elderly ACI patients at 3 months after intravenous thrombolytic therapy.
