Analysis of risk factors for respiratory failure in Klebsiella pneumoniae pneumonia
10.3969/j.issn.1673-9701.2025.32.003
- VernacularTitle:肺炎克雷伯菌肺炎并发呼吸衰竭的危险因素分析
- Author:
Xuewen DU
1
;
Chunfeng WU
;
Yongjie WANG
Author Information
1. 长春中医药大学临床医学院,吉林长春 130117
- Publication Type:Journal Article
- Keywords:
Klebsiella pneumoniae;
Respiratory failure;
Pneumonia;
Risk factors
- From:
China Modern Doctor
2025;63(32):8-11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the risk factors of respiratory failure(RF)in patients with Klebsiella pneumoniae pneumonia(KPN).Methods A total of 79 KPN patients admitted to Jilin Provincial People's Hospital from July 2023 to July 2024 were selected as subjects.Patients were divided into RF group(n=42)and non-RF group(n=37)based on RF comorbidity status.Independent risk factors for RF comorbidity were identified through univariate analysis and multivariate Logistic regression,with model predictive performance evaluated using receiver operating characteristic(ROC)curve.Results Compared to non-RF group,serum procalcitonin(PCT)levels were higher and serum albumin(ALB)and oxygenation index were lower in RF group(P＜0.05).Univariate analysis identified age,bedridden status,number of comorbidities,PCT,oxygenation index,ALB,multi-lobar infiltration,and mechanical ventilation as significant predictors of RF development in KPN patients.Multivariate Logistic analysis showed that elevated PCT levels,decreased oxygenation index,and reduced ALB were independent risk factors for RF in KPN patients,with area under the ROC curve of predictive model being 0.884.Conclusion When blood PCT is elevated,blood ALB is reduced,and the oxygenation index is decreased,the likelihood of RF in KPN patients is significantly increased.
