Clinical effects of Modified Shashen Maidong Decoction combined with western medicines on patients with pediatric Mycoplasma pneumoniae pneumonia due to Yin Deficiency and Lung Heat Pattern
10.3969/j.issn.1001-1528.2025.11.015
- VernacularTitle:沙参麦冬汤加减联合西药对阴虚肺热型小儿肺炎支原体肺炎患者的临床疗效
- Author:
Yu DING
1
;
Yi-qun TENG
1
Author Information
1. 浙江中医药大学,浙江 杭州 310000;嘉兴大学附属第二医院儿科,浙江嘉兴 314099
- Publication Type:Journal Article
- Keywords:
Shashen Maidong Decoction;
Cefuroxime;
Minocycline Hydrochloride;
pediatric Mycoplasma pneumoniae pneumonia;
Yin Deficiency and Lung Heat
- From:
Chinese Traditional Patent Medicine
2025;47(11):3635-3639
- CountryChina
- Language:Chinese
-
Abstract:
AIM To explore the clinical effects of Modified Shashen Maidong Decoction combined with western medicines on patients with pediatric Mycoplasma pneumoniae pneumonia due to Yin Deficiency and Lung Heat Pattern.METHODS Ninety-eight patients were randomly assigned into control group(49 cases)for 7-day administration of Cefuroxime and Minocycline Hydrochloride,and observation group(49 cases)for 7-day administration of Modified Shashen Maidong Decoction,Cefuroxime and Minocycline Hydrochloride.The changes in symptom relief time,inflammatory factors(CRP,IL-6,TNF-α),blood gas indices(SaO2,PaO2,PaCO2),T lymphocyte subsets(CD3+,CD4+,CD8+),TCM syndrome scores,pulmonary function indices(PEF,FVC,FEV1)and incidence of adverse reactions were detected.RESULTS The observation group demonstrated shorter symptom relief time(P＜0.05).After the treatment,the two groups displayed decreased inflammatory factors,PaCO2,CD8+,TCM syndrome scores(P＜0.05),and increased SaO2,PaO2,CD3+,CD4+(P＜0.05),especially for the observation group(P＜0.05).No significant difference in incidence of adverse reactions was found between the two groups(P＞0.05).CONCLUSION For the patients with pediatric Mycoplasma pneumoniae pneumonia due to Yin Deficiency and Lung Heat Pattern,Modified Shashen Maidong Decoction combined with western medicines can safely and effectively improve clinical symptoms and lung functions.
