Analysis of volatile components in Yinhu Ganmao Powder by GC-MS/MS and content determination of nineteen constituents
10.3969/j.issn.1001-1528.2025.11.002
- VernacularTitle:GC-MS/MS法分析银胡感冒散挥发性成分及19种成分含量测定
- Author:
Li-jun DENG
1
;
Jin-feng LI
;
Xi-ya GUO
;
Xin-yi HU
;
Zhi-heng SU
;
Dan-feng LI
Author Information
1. 广西医科大学药学院,广西南宁 530021;广西壮族自治区妇幼保健院,广西南宁 530021
- Publication Type:Journal Article
- Keywords:
Yinhu Ganmao Powder;
volatile components;
qualitative analysis;
content determination;
GC-MS/MS
- From:
Chinese Traditional Patent Medicine
2025;47(11):3540-3548
- CountryChina
- Language:Chinese
-
Abstract:
AIM To establish a GC-MS/MS method for the analysis of volatile components in Yinhu Ganmao Powder,and to determine the contents of α-pinene,camphene,sabinene,β-pinene,α-terpinene,(+)-limonene,p-cymene,1,8-cineole,linalool,L-menthol,terpinen-4-ol,DL-menthol,α-terpineol,tridecane,pulegone,caryophyllene,humulene,n-hexadecane and patchouli alcohol.METHODS The analysis was performed on a DB-624 UI capillary column(30 m×0.25 mm×1.40 μm ),and electron ionization source was adopted with multiple reaction monitoring mode.RESULTS Fifty volatile components and twenty-five liposoluble components were identified in volatile oils and medicinal material powder,respectively.Nineteen constituents showed good linear relationships within their own ranges(r ≥ 0.999 0),whose average recoveries were 84.43％-113.31％with the RSDs of less than 9.15％.CONCLUSION This stable,accurate and reproducible method can provide a reference for the quality evaluation of Yinhu Ganmao Powder.
