Clinical effectiveness of Wuhuang Shengji Decoction irrigation combined with incision and hanging suture in treatment of patients with perianal abscess
10.11816/cn.ni.2025-242205
- VernacularTitle:五黄生肌方冲洗联合切开挂线术治疗肛周脓肿的临床疗效
- Author:
Yingming QIAN
1
;
Jin XU
1
;
Liming HUANG
1
;
Yanwu LU
1
Author Information
1. 宁波市中医院中医外科,浙江 宁波 315010
- Publication Type:Journal Article
- Keywords:
Wuhuang Shengji Decoction;
Incision and hanging suture;
Perianal abscess;
Vascular endothelial growth factor;
Platelet derived endothelial cell growth factor
- From:
Chinese Journal of Nosocomiology
2025;35(15):2305-2309
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To explore the clinical efficacy of Wuhuang Shengji decoction irrigation combined with inci-sion and hanging suture in patients with perianal abscess.METHODS A total of 121 patients with perianal abscess admitted to the Anorectal Department of Ningbo Traditional Chinese Medicine Hospital from Jan.2022 to Jan.2024 were selected as the study subjects.According to the treatment methods,they were divided into a control group(n=37),a positive control group(n=41)anda research group(n=43).The control group was treated with incision and hanging suture,the positive control group was treated with recombinant human epidermal growth factor combined with incision and hanging suture,and the research group was treated with Wuhuang Shengji Decoction irrigation combined with incision and hanging suture.The clinical efficacy,the time of necrotic tissue shedding,new skin appearing,wound itch disappearing and wound healing and the recurrence rate were ob-served.The visual analogue scale(VAS),wound secretion score and expression levels of vascular endothelial growth factor(VEGF)and platelet-derived endothelial cell growth factor(PD-ECGF)in wound secretions were compared before and 14 days after treatment in the three groups.RESULTS The clinical efficacy of the study group(90.70%)was higher than that of the positive control group(87.80%)and control group(70.27%);the recur-rence rate of the study group(2.33%)was lower than that of the positive control group(9.76%)and the control group(18.92%),and the differences were statistically significant(P<0.05).The time required for necrotic tissue shedding,new skin appearing,wound itch disappearing and wound healing followed the trend of study group
