Research progress on monkeypox virus infection during pregnancy
10.11816/cn.ni.2025-246609
- VernacularTitle:妊娠期猴痘病毒感染研究进展
- Author:
Shaohua LI
1
;
Xiuying NI
;
Yuyan SUN
Author Information
1. 山东第二医科大学附属益都中心医院神经内科,山东 潍坊 262500
- Publication Type:Journal Article
- Keywords:
Monkeypox virus;
Pregnancy;
Abortion;
Stillbirth;
Research progress
- From:
Chinese Journal of Nosocomiology
2025;35(15):2390-2394
- CountryChina
- Language:Chinese
-
Abstract:
Monkeypox is a zoonotic disease caused by the monkeypox virus(MPXV),which belongs to the or-thopoxvirus genus along with the smallpox virus.In Jul.2022 and Aug.2024,the World Health Organization(WHO)declared monkeypox outbreaks"public health emergencies of international concern"twice.The virus pri-marily spreads through close contact,which can be transmitted from infected animals to humans and among hu-mans.Pregnant women are susceptible to MPXV,and the virus can be transmitted vertically to the fetus through the placenta,with trophoblastic cells in the placenta considered to be the targets for MPXV replication.MPVX in-fection during pregnancy may lead to adverse pregnancy outcomes such as miscarriage,premature birth and fetal death,and the clinical treatment outcomes are closely associated with the subtype of the virus.The diagnosis of monkeypox mainly relies on MPXV DNA test.To prevent monkeypox,women who are at the childbearing age should complete the vaccination before the pregnancy and avoid contacting with the patients with monkeypox or the animals that may carry MPXV.
