Analysis of distribution characteristics and drug resistance of mucous and non-mucous Streptococcus pneumoniae infections
10.3969/j.issn.1673-9701.2025.22.011
- VernacularTitle:黏液型与非黏液型肺炎链球菌感染分布特征及耐药性分析
- Author:
Yun XIANG
1
;
Yuanhui SU
1
;
Chunhong XIE
1
;
Huiju ZHANG
1
;
Yanqin NIE
1
;
Xing CHEN
1
;
Lianjiang HUANG
1
Author Information
1. 厦门医学院附属第二医院检验科,福建厦门 361021
- Publication Type:Journal Article
- Keywords:
Streptococcus pneumoniae;
Mucous;
Non-mucous;
Drug resistance
- From:
China Modern Doctor
2025;63(22):45-48,68
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the distribution characteristics and drug resistance of mucous and non-mucous Streptococcus pneumoniae(SP).Methods SP isolated from clinical specimens of the Second Affiliated Hospital of Xiamen Medical College from January 2023 to June 2024 were collected.They were isolated,cultured and identified,and their susceptibility to antibacterial drugs was determined.Results A total of 291 SP strains were isolated,of which 20 strains were mucous SP and 271 strains were non-mucous SP.Children played a dominant role of non-mucous SP infection,but mucous SP mainly infected adults and the children above 5 years old.Both phenotypes of SP were mainly characterized by pulmonary infection.Non-mucous SP had a relatively high sensitivity rate to vancomycin,linezolid,penicillin,ertapenem,chloramphenicol,levofloxacin,moxifloxacin and ofloxacin.It had a high resistance rate to compound sulfamethoxazole,clindamycin,erythromycin and tetracycline.Mucous SP was completely sensitive to penicillin,amoxicillin,cefotaxime,ceftriaxone,ertapenem,vancomycin,linezolid,levofloxacin and moxifloxacin,and had a relatively high resistance rate to clindamycin,erythromycin and tetracycline.Conclusion The laboratory should enhance the detection capacity of mucous SP.Mucous SP is highly sensitive to common antibiotics.Clinicians should select antibiotics based on drug sensitivity results to delay the occurrence of drug resistance.
