Investigation and management of suspected hospital-acquired outbreak of Serratia marcescens infection in neonatal intensive care unit of a three-A hospital
10.11816/cn.ni.2025-258022
- VernacularTitle:某三甲医院新生儿重症监护病房疑似黏质沙雷菌医院感染暴发调查与处置
- Author:
Liping WU
1
;
Junlin YANG
1
;
Xi YANG
1
;
Guangying LUO
1
;
Zhuhong ZHA
1
Author Information
1. 贵州医科大学附属医院医院感染管理科,贵州贵阳 550004
- Publication Type:Journal Article
- Keywords:
Neonatal intensive care unit;
Suspected hospital-acquired infection outbreak;
Serratia marcescens;
Hospital-acquired infection;
Prevention and control measures
- From:
Chinese Journal of Nosocomiology
2025;35(16):2422-2426
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To analyze the investigation and handling process of a suspected outbreak of hospital-ac-quired Serratia marcescens infection in the Neonatal Intensive Care Unit(NICU)of a certain hospital,and to pro-vide valuable reference for the prevention and control of hospital-acquired infections.METHODS An epidemiologi-cal investigation was conducted on three S.marcescens-positive neonates admitted to the NICU of the Affiliated Hospital of Guizhou Medical University from Oct.12 to 18,2024.Environmental hygiene sampling was carried out on the surfaces of the ward.The homology of the strains was analyzed,and effective intervention measures were taken.RESULTS The incidence of S.marcescens sepsis in the NICU from Oct.12 to 18,2024 was 2.20％(2/91)compared to 2.35％in the same period of 2023(2/85),no significant difference was found between the two time periods(P=0.946).Among the three S.marcescens-positive NICU neonates,one was considered com-munity-acquired,while the other two were diagnosed with S.marcescens sepsis.A total of 59 environmental hy-giene samples were collected,with one sample detecting S.marcescens in the bedside infusion pump slot of case 1.The homology analysis results showed high homology among the four S.marcescens strains but not completely homologous.After effective preventive and control measures were implemented,suspected S.marcescens cluste-ring events didn't further occurred.CONCLUSION The occurrence of this incident may be attributed to inadequate cleaning and disinfection of environmental surfaces and improper hand hygiene practices by some medical staff.
