Impact of sublingual nitroglycerin on imaging quality of non-contrast MR coronary angiography
10.13929/j.issn.1003-3289.2025.10.027
- VernacularTitle:舌下含服硝酸甘油对无对比剂MR冠状动脉血管成像效果的影响
- Author:
Xiankuo HU
1
;
Yang ZHANG
;
Yushan YUAN
;
Lei ZHANG
;
Peiqi MA
;
Xiaohu LI
Author Information
1. 阜阳市人民医院影像中心,安徽阜阳 236000
- Publication Type:Journal Article
- Keywords:
coronary disease;
coronary angiography;
magnetic resonance imaging;
nitroglycerin;
prospective studies
- From:
Chinese Journal of Medical Imaging Technology
2025;41(10):1730-1734
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the impact of sublingual nitroglycerin(NTG)on imaging quality of non-contrast MR coronary angiography(NMRCA).Methods Thirty patients with suspected coronary heart disease(CHD)who would undergo coronary angiography(CAG)examination were prospectively collected.NMRCA images were acquired before and after sublingual NTG.Clinical meaningful stenosis was defined as CAG showed luminal stenosis ≥50％.Then imaging quality scores,diameters and display length of coronary arteries,as well as the impact of NTG on diagnostic performances of NMRCA for coronary artery stenosis were compared between images before and after administration of NTG.Results After administration of NTG,image quality of left main(LM)-left anterior descending artery(LAD)and left circumflex artery(LCX),as well as the proximal,mid and distal segments of LAD and distal segment of LCX significantly improved(all P＜0.05).No significant difference of visible coronary artery length was noticed before and after administration of NTG(all P＞0.05).After administration of NTG,diameter of right coronary artery(RCA),LM-LAD and LCX increased(all P＜0.05),with dilation rate of 16.23％(13.57％,19.17％),17.52％(12.69％,21.11％)and 14.30％(7.62％,23.22％),respectively,while the sensitivity,specificity,accuracy and negative predictive value of NMRCA for diagnosing coronary artery stenosis improved(all P＜0.05).Conclusion Sublingual NTG could improve imaging quality of NMRCA and increase its efficacy for diagnosing coronary artery stenosis.
