Diffusion-weighted imaging,amide proton transfer-weighted imaging and glucose chemical exchange saturation transfer imaging for predicting lymph node metastasis of rectal cancer
10.13929/j.issn.1003-3289.2025.10.019
- VernacularTitle:基于弥散加权成像、酰胺质子转移加权成像及葡萄糖化学交换饱和转移成像预测直肠癌淋巴结转移
- Author:
Lei SHEN
1
;
Fangfang FU
1
;
Bo DAI
1
;
Tianyun YANG
1
;
Shewei DOU
1
Author Information
1. 河南省人民医院放射科,河南郑州 450003
- Publication Type:Journal Article
- Keywords:
rectal neoplasms;
lymphatic metastasis;
magnetic resonance imaging;
chemical exchange saturation transfer
- From:
Chinese Journal of Medical Imaging Technology
2025;41(10):1696-1700
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of diffusion-weighted imaging(DWI),amide proton transfer-weighted imaging(APTWI)and glucose chemical exchange saturation transfer imaging(glucoCEST)for predicting lymph node metastasis of rectal cancer.Methods Sixty cases of rectal cancer confirmed by pathology were retrospectively enrolled and divided into metastasis group(n=36)and non-metastasis group(n=24)based on the presence or absence of lymph node metastasis.The apparent diffusion coefficient(ADC)value,as well as the values of magnetization transfer ratio asymmetry at 3.50 ppm and 1.20 ppm(MTRasym3.50 ppm and MTRasym1.20ppm)of the lesions were respectively obtained based on DWI,APTWI and glucoCEST and then compared between groups.Receiver operating characteristic curve was drawn,the area under the curve(AUC)was calculated to evaluate the efficacy of each parameter alone and their combination for predicting lymph node metastasis of rectal cancer.Results In metastasis group,ADC value of the lesions was lower,while MTRasym3.50 ppm and MTRasym1.20 ppm values were both higher than those in non-metastasis group(all P＜0.05).AUC of the combination of the above parameters for predicting lymph node metastasis of rectal cancer based on ADC,MTRasym3.50ppm and MTRasym1.20 ppm values was 0.970,significantly higher than that of each single parameter(0.858,0.804 and 0.755,respectively;Z=2.442-3.231,all P＜0.05).Conclusion DWI,APTWI and glucoCEST could all be used to predicte lymph node metastasis of rectal cancer.Combination of ADC,MTRasym3.50 ppm and MTRasym1.20 ppm had the highest predictive efficacy.
