Nomogram based on conventional ultrasonic manifestations for predicting malignant risk of breast non-mass lesions
10.13929/j.issn.1003-3289.2025.10.015
- VernacularTitle:基于常规超声表现的列线图预测乳腺非肿块型病变恶性风险
- Author:
Jin JIN
1
;
Wei ZHANG
1
;
Wen HE
1
;
Tengfei YU
1
;
Linggang CHENG
1
Author Information
1. 首都医科大学附属北京天坛医院超声科,北京 100070
- Publication Type:Journal Article
- Keywords:
breast neoplasms;
ultrasonography,mammary;
diagnosis,differential;
nomograms
- From:
Chinese Journal of Medical Imaging Technology
2025;41(10):1677-1681
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy of a nomogram based on conventional ultrasonic manifestations for predicting malignant risk of breast non-mass lesions(NML).Methods A total of 120 NML diagnosed with ultrasound in 113 female patients were retrospectively included and divided into malignant group(n=44)and benign group(n=76)based on pathological results.Patients' age,ultrasonic manifestations of NML and ipsilateral axillary lymph node were compared between groups.Then a nomogram was constructed using a multivariable logistic regression model,and its diagnostic performance and accuracy were validated.Results The ratios of patients' aged≥45 years,with abnormal ipsilateral axillary lymph nodes,NML with maximum diameter≥2 cm,posterior echo attenuation,rich blood flow signals,architectural distortion and microcalcification were significantly different between groups(all P＜0.05).Patient's age≥45 years,with abnormal ipsilateral axillary lymph nodes,and NML with rich blood flow signals,architectural distortion and microcalcification were all independent predictive factors for high malignant risk of breast NML(all P＜0.05).The constructed nomogram achieved an area under the receiver operating characteristic curve of 0.901 for predicting malignant risk of breast NML,and its predicting probabilities demonstrated good agreement with the actual probabilities(Hosmer-Lemeshow test P＞0.05).Conclusion The nomogram incorporating patient's age,ultrasonic manifestations of NML and ipsilateral axillary lymph node could effectively quantify malignancy risk of breast NML.
