Observation on changes of left ventricular systolic function in children with sepsis based on two-dimensional speckle tracking imaging
10.13929/j.issn.1003-3289.2025.10.013
- VernacularTitle:基于二维斑点追踪成像观察脓毒症患儿左心室收缩功能变化
- Author:
Ye XIONG
1
;
Huan ZHOU
1
;
Jing PENG
1
;
Xiaoyuan FENG
1
Author Information
1. 华中科技大学同济医学院附属武汉儿童医院心脏超声室,湖北武汉 430000
- Publication Type:Journal Article
- Keywords:
child;
sepsis;
ventricular function,left;
echocardiography
- From:
Chinese Journal of Medical Imaging Technology
2025;41(10):1667-1671
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of left ventricular systolic function in children with sepsis by two-dimensional speckle tracking imaging(2D-STI).Methods A total of 29 children with sepsis were retrospectively enrolled and divided into severe sepsis group(n=10)and non-severe sepsis group(n=19)according to relevant diagnostic criteria,while 21 healthy children were taken as controls(control group).Conventional echocardiographic parameters and 2D-STI parameters were compared among 3 groups and between each 2 groups.Results Significant differences of left atrial diameter(LAD),left ventricular end-diastolic diameter(LVEDD)and right atrial diameter(RAD)were found among 3 groups(all P＜0.05),while no significant difference of right ventricular end-diastolic diameter(RVEDD)nor left ventricular ejection fraction(LVEF)was noticed(both P＞0.05).Meanwhile,significant differences of left ventricular global longitudinal strain(LVGLS)and basal anterior(BA),basal anterolateral(BAL),basal inferolateral(BIL),mid-anterior(MA),mid-anterolateral(MAL),mid-inferolateral(MIL),apical anterior(APA),apical lateral(APL),apical inferior(API)and apex cap(APEX)segment longitudinal strain(LS)were found among 3 groups(all P＜0.05),also of LVGLS between each 2 groups,of LS in BAL,BIL,MA,MAL,MIL,APA,APL,API and APEX segments between severe sepsis group and control group,of LS in BAL and MAL segments between non-severe sepsis group and control group,and of LS in BA,M A,APL,API and APEX segments between severe sepsis group and non-severe sepsis group(all P＜0.05).Conclusion Left ventricular 2D-STI parameters in children with sepsis changed when LVEF was still in normal range,and some parameters were related to the severity of disease.
