Prone-position MRI of lumbar spine for diagnosing pediatric occult tethered cord syndrome
10.13929/j.issn.1003-3289.2025.10.006
- VernacularTitle:俯卧位腰椎MRI用于诊断儿童隐匿型脊髓栓系综合征
- Author:
Jie LI
1
;
Yurong MA
;
Wanjun HU
;
Na HAN
;
Songhong YUE
;
Tiejun GAN
;
Guangyao LIU
;
Shuai YUAN
;
Jing ZHANG
Author Information
1. 兰州大学第二医院(第二临床医学院)核磁共振科,甘肃兰州 730030;甘肃省分子及功能影像临床医学研究中心,甘肃兰州 730030;甘肃省医用核磁共振装备应用行业技术中心,甘肃兰州 730030
- Publication Type:Journal Article
- Keywords:
neural tube defects;
magnetic resonance imaging;
prone position;
prospective studies
- From:
Chinese Journal of Medical Imaging Technology
2025;41(10):1641-1645
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of prone-position MRI of lumbar spine for diagnosing pediatric occult tethered cord syndrome(OTCS).Methods A total of 67 children with suspected tethered cord syndrome(TCS)and confirmed OTCS by surgery were prospectively enrolled as OTCS group,while 73 healthy subjects were recruited as control group.Supine-and prone-position lumbar MR examinations were performed in both groups.The position of filum terminale on prone axial T2WI and the presence or absence of"sunset sign"(i.e.filum terminale located within the dorsal 1/2 of spinal canal on prone axial T2WI)were observed,spinal cord conus mobility was calculated.The efficacy of"sunset sign"for diagnosing OTCS in children was calculated through comparison between groups.Receiver operating characteristic curve was drawn,the area under the curve(AUC)was calculated to evaluate the diagnostic efficacy of spinal cord conus mobility.Results On prone-position axial T2WI,"sunset sign"was found in 58 cases(58/67,86.57％)but not in 9 cases(9/67,13.43％)in OTCS group,which was not even observed in control group.The sensitivity of"sunset sign"for diagnosing pediatric OTCS was 86.57％(58/67),with specificity of 100％(73/73),positive predictive value of 100％(58/58)and negative predictive value of 89.02％(73/82).The spinal cord conus mobility was(19.30±5.89)％in OTCS group and(31.71±6.58)％in control group,being statistically different between groups(t=-11.722,P＜0.001).The sensitivity,specificity and AUC of spinal cord conus mobility for diagnosing pediatric OTCS was 80.60％,90.41％and 0.920,respectively.Conclusion Prone-position MRI of lumbar spine could be used in diagnosing pediatric OTCS.
