Advances in the study of the role of T cells in acute kidney injury
10.3760/cma.j.cn101721-20241108-00365
- VernacularTitle:T细胞在急性肾损伤中的作用研究进展
- Author:
Yaoyao GAO
1
;
Guozhen ZHU
1
Author Information
1. 山西医科大学第二医院肾内科，太原 030001
- Publication Type:Journal Article
- Keywords:
Acute kidney injury;
T cells;
Repair
- From:
Clinical Medicine of China
2025;41(3):235-240
- CountryChina
- Language:Chinese
-
Abstract:
Acute kidney injury(AKI)is a common clinical syndrome characterized by high morbidity and mortality.It's pathogenesis is complex and involves multiple pathophysiological processes,including inflammatory responses,oxidative stress,mitochondrial dysfunction,apoptosis,and immune dysregulation. Recent studies had shown that AKI is an independent risk factor for the development and progression of chronic kidney disease(CKD), significantly impacting patient outcomes. As key effector cells in the immune response, T cells play a crucial role throughout the onset, progression and repair phases of AKI.
