The modern pharmacological effects of Yujin and its research progress in neurodegenerative diseases
10.3760/cma.j.cn101721-20250325-00139
- VernacularTitle:郁金的现代药理作用及其在神经退行性疾病中的研究进展
- Author:
Xuemei SUN
1
;
Zhenying ZHAO
1
;
Fengkun YANG
1
Author Information
1. 天津市人民医院 南开大学第一附属医院药学部，天津 300121
- Publication Type:Journal Article
- Keywords:
Neurodegenerative diseases;
Curcuma aromatica;
Mechanism of action;
Inflammation;
Bioavailability
- From:
Clinical Medicine of China
2025;41(3):227-234
- CountryChina
- Language:Chinese
-
Abstract:
The active ingredients of Curcuma aromatica have multi-target effects and could intervene in the process of neurodegenerative diseases from multiple perspectives, such as promoting the clearance of Aβ, anti-inflammatory, anti-oxidant, neuroprotective, anti-depressant, and anti-tumor effects. However, the low bioavailability of Curcuma extracts limits their therapeutic effects in the body. In addition, the side effects of long-term use and the dose-effect relationship are still unclear, and more new pharmacodynamic observations are needed. This article reviews the research on single-ingredient and compound traditional Chinese medicine preparations of Curcuma to provide references for clinical medication.
