Research development on genetic background and immune characteristics of latent autoimmune diabetes in adults
10.3760/cma.j.cn101721-20250113-00025
- VernacularTitle:成人隐匿性自身免疫性糖尿病的遗传背景及免疫特性研究进展
- Author:
Luyang YANG
1
;
Yunfeng LIU
;
Ru LI
;
Jing YANG
Author Information
1. 山西医科大学第一医院内分泌科,太原 030001
- Publication Type:Journal Article
- Keywords:
Latent autoimmune diabetes;
Human leukocyte antigen;
ncRNA;
Cell-mediated immunity;
Humoral immunity;
Innate immune response
- From:
Clinical Medicine of China
2025;41(3):222-226
- CountryChina
- Language:Chinese
-
Abstract:
Latent autoimmune diabetes in adults (LADA) is a type of mixed diabetes in WHO2019 Diabetes classification. LADA has both type 1 diabetes and type 2 diabetes genetic susceptibility genes. It is difficult to distinguish LADA from type 1 diabetes mellitus and type 2 diabetes mellitus. This paper systematically reviewed the genetic background and immune characteristics of LADA, providing new ideas for the study of LADA and theoretical support for the precise diagnosis and treatment of LADA and immune intervention strategies.