Research progress of Vitamin D in chronic rhinosinusitis with nasal polyps
10.3760/cma.j.cn101721-20240922-00301
- VernacularTitle:维生素D与伴鼻息肉型慢性鼻窦炎的研究进展
- Author:
Xinru LI
1
;
Jian MA
1
Author Information
1. 南京医科大学附属南京医院 南京市第一医院耳鼻咽喉头颈外科，南京 210006
- Publication Type:Journal Article
- Keywords:
Chronic rhinosinusitis;
Nasal polyps;
Vitamin D;
Organizational restructuring;
Innate immunity;
Adaptive immunity
- From:
Clinical Medicine of China
2025;41(1):76-80
- CountryChina
- Language:Chinese
-
Abstract:
Chronic rhinosinusitis with nasal polyps is a common chronic inflammatory disease involving the nasal cavity and paranasal sinuses, with unknown etiology and poor clinical treatment effect. In addition to calcium and phosphorus metabolism, vitamin D is involved in immune modulation and anti-inflammatory responses. We review recent research on the improvement of tissue remodeling, innate and adaptive immune changes caused by long-term chronic inflammation with vitamin D, and summarizes the effects and molecular mechanisms of vitamin D on the inflammatory process of sinusitis.
