Based on data mining to explore the medication rules of traditional Chinese medicine in the treatment of postpartum depression
10.3969/j.issn.1673-9701.2025.15.011
- VernacularTitle:基于数据挖掘探讨中医药治疗产后抑郁的用药规律
- Author:
Feixia LI
1
;
Hong ZHAO
1
;
Qian ZHU
1
;
Xiaoyan WU
1
;
Hua MIAO
1
Author Information
1. 陕西中医药大学第二附属医院产科,陕西 咸阳 712000
- Publication Type:Journal Article
- Keywords:
Data mining;
Traditional Chinese medicine;
Postpartum depression;
Medication regularity
- From:
China Modern Doctor
2025;63(15):51-55
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the main composition,four Qi,five tastes,meridian tropism and medication ideas of traditional Chinese medicine in the treatment of postpartum depression(PPD).Methods Literature on clinical efficacy studies of PPD treatment with traditional Chinese medicine published in China National Knowledge Infrastructure,Wanfang Data Knowledge Service Platform,VIP,Embase,Web of Science,PubMed databases from October 30,2004 to October 30,2024 was retrieved.The count frequency,four Qi,five tastes and meridian tropism of the selected Chinese medicine were carried out,and the association rule analysis was carried out to explore the prescription drug rule of Chinese medicine in the treatment of PPD.Results A total of 71 relevant literatures were selected,including 71 prescriptions and 96 flavors of Chinese medicine.27 of the high-frequency drugs with a frequency of more than 10％were selected.The top 8 core drugs in the frequency of Chinese medicine were Chaihu,Danggui,Gancao,Baishao,Fuling,Baizhu,Suanzaoren and Yujin,followed by Chuanxiong,Yuanzhi,Xiangfu,Huangqi,Dazao and Hehuanpi.Among all the core drugs,the four Qi are mainly warm and peaceful drugs,the five tastes are mainly sweet,bitter and pungent,and the spleen channel and liver channel are mainly.The main drug effects were Qi-tonifying drugs,tranquilizing drugs,blood-activating drugs for removing blood stasis,followed by blood-tonifying drugs,Qi-promoting drugs,wind-heat dispersing drugs,liver-calming drugs.Chaihu,Danggui,Baishao and Fuling were the four most relevant Chinese medicines.Conclusion The main pathogenesis of PPD is liver-Qi and spleen-deficiency,which is located in the liver and spleen.Clinical treatment is mainly based on soothing liver-Qi and resolving depression,invigorating spleen and nourishing blood,and supplemented with Qi-nourishing heart-calming drugs.
