Comparison of analgesic effects of continuous femoral nerve block with different concentrations of ropivacaine in total knee arthroplasty in women
10.3969/j.issn.1673-9701.2025.14.011
- VernacularTitle:不同浓度罗哌卡因连续收肌管阻滞在女性全膝关节置换术中的镇痛效果比较
- Author:
Jiahui TU
1
;
Zhanfeng ZHANG
Author Information
1. 湖州市第一人民医院麻醉科,浙江 湖州 313000
- Publication Type:Journal Article
- Keywords:
Ultrasound;
Total knee arthroplasty;
Continuous femoral nerve block;
Ropivacaine
- From:
China Modern Doctor
2025;63(14):44-48
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the analgesic effects of different concentrations of ropivacaine combined with ultrasound-guided nerve stimulation for continuous femoral nerve block(CFNB)in elderly female patients undergoing total knee arthroplasty(TKA).Methods A total of 90 female patients scheduled for TKA at the First People's Hospital of Huzhou from March 2023 to February 2024 were selected as the research subjects,they were randomly divided into three groups(A,B,C)using a random number table,with 30 cases in each group.Different concentrations of ropivacaine(20ml)were administered for muscle relaxant block before general anesthesia:Group A received 0.150％ropivacaine,group B received 0.250％ropivacaine,and group C received 0.375％ropivacaine.Postoperatively,analgesia pumps with the corresponding concentration of local anesthetic were set at 5ml/h for 72h.Intraoperative hemodynamic changes were recorded,postoperative visual analog pain scores(VAS)during rest,active,and continuous passive functional training,time to first ambulation,popliteal discomfort,muscle strength grading,and adverse reactions were assessed.Results VAS scores during active functional training at 24h,48h,and 72h among three groups showed statistically significant differences(P<0.05),with group C having significantly lower VAS scores than groups A and B(P<0.05).VAS scores for passive training at 72h also showed significant differences,with group C scoring significantly lower than groups A and B(P<0.05).The proportion of patients taking more than 24h to ambulate for the first time and proportion experiencing popliteal discomfort differed among the groups,with group C having significantly fewer cases than groups A and B.Muscle strength in all groups was greater than grade 3 from 24h to 72h postoperatively.Conclusion CFNB with 0.375％ropivacaine has a good postoperative analgesic effect for TKA and does not increase incidence of side effects.
