Advancements in comprehensive treatment strategies for esophageal cancer
10.12354/j.issn.1000-8179.2025.20250096
- VernacularTitle:食管癌综合治疗进展
- Author:
Zheng ZIYU
1
;
Wang XIN
1
Author Information
1. 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科(北京市 100021)
- Publication Type:Journal Article
- Keywords:
esophageal cancer;
chemoradiotherapy;
immunotherapy
- From:
Chinese Journal of Clinical Oncology
2025;52(6):298-303
- CountryChina
- Language:Chinese
-
Abstract:
Esophageal cancer is a common malignant tumor of the digestive system that exhibits high morbidity and mortality rates in China.Multidisciplinary treatment regimens have improved patient survival,but the 5-year survival rate remains low.Challenges including posttreatment organ dysfunction,reduced quality of life,and high recurrence rates continue to impose a significant disease burden.Radio-therapy plays an important role in the treatment of esophageal cancer at all stages.Built upon advances in radiotherapy techniques,devel-opment of new drugs,and emergence of novel monitoring methods,current therapeutic strategies and research are increasingly focused on refining patient subgroups to deliver individualized treatments with low-toxicity and high efficacy.In this article,we review advances in ra-diotherapy for esophageal cancer between 2023 to 2024,focusing on organ preservation strategies,progress in neoadjuvant and definitive therapies,treatment for recurrent or metastatic esophageal cancers,control of side effects during radiotherapy,and methods to predict the efficacy of radiotherapy.
