Chemical constituents from Pyrolae Herba and their inhibitory activity against pathogenic bacteria associated with sports injuries
10.3969/j.issn.1001-1528.2025.05.017
- VernacularTitle:鹿衔草化学成分及其运动损伤易感染病原菌抑制活性研究
- Author:
Ya-li LIU
1
;
Shao-wen LIU
;
Yu WANG
;
Yi ZHANG
;
Ji-hong WANG
;
Xiao-huan ZHOU
;
Su-li MA
Author Information
1. 广东石油化工学院,广东茂名 525000
- Publication Type:Journal Article
- Keywords:
Pyrolae Herba;
chemical constituents;
isolation and identification;
sports injuries;
pathogenic bacteria
- From:
Chinese Traditional Patent Medicine
2025;47(5):1524-1530
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the chemical constituents from Pyrolae Herba and their activity against pathogenic bacteria associated with sports injuries.METHODS Silica gel and Sephadex LH-20 were used for isolation and purification,then the structures of obtained compounds were identified by physicochemical properties and spectral data.The antibacterial activity was detected by filter paper method.RESULTS Twenty five compounds were isolated and identified as manuleoside H(1),5-hydroxy-3,7-dimethoxy-4,-methyl flavone(2),5-hydroxy-3,7,4'-methoxy-flavone(3),5-hydroxy-7,3',4'-trimethoxy-flavone(4),5,7-dihydroxy-3-methoxy-flavone(5),7.5,4'-trihydroxyflavone(6),ethyl vanillate(7),clovandiol(8),hydroxydihydrobovolide(9),zanthopyranone(10),eugenin(11),berchemol(12),3,7-dimethoxy-5,3',4'-trihydroxyflavone(13),2,5-dimethyl-7-hydroxychromone(14),rutalinium(15),formononetin(16),8-hydroxy-4',7-dimethoxy-isoflavones(17),isoline(18),dearabinosyl pneumonanthoside(19),3,5-dihydroxycinnamic acid(20),2,4,6-trihydroxyacetophenone(21),p-isopropyl benzoic acid(22),geraldone(23),ethylsyringin(24),4-hydroxyphenylethyl-2'-hydroxypropionate(25).Compounds 8,10,12,16 and 24 showed bacteriostatic zone on pathogenic bacteria susceptible to sports injuries.CONCLUSION All the compounds are isolated from Pyrolae Herba for the first time.Compounds 8,10,12,16 and 24 have inhibitory activity against pathogenic bacteria susceptible to sports injuries.
