Exploration on medication rules of national patents of traditional Chinese medicine compound for prevention and treatment of urinary tract infection based on R language data mining
10.3969/j.issn.1673-9701.2025.21.013
- VernacularTitle:基于R语言数据挖掘探究国家专利中药复方防治尿路感染的用药规律
- Author:
Chenyang PEI
1
;
Guanghui ZHONG
;
Yuwei SONG
;
Chenchen WANG
;
Qingyun MAO
;
Rongrong ZHANG
;
Xin XU
;
Yifan WAN
Author Information
1. 浙江中医药大学宁波临床医学院,浙江宁波 315010
- Publication Type:Journal Article
- Keywords:
Urinary tract infection;
National patent;
R language;
Data mining;
Medication rule
- From:
China Modern Doctor
2025;63(21):56-60,95
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the medication rules of traditional Chinese medicine compound patents for the prevention and treatment of urinary tract infection(UTI)through data mining technology.Methods The patents of traditional Chinese medicine compounds for the prevention and treatment of UTI in patent announcement module of China National Intellectual Property Administration website as data sources.The statistical analysis platforms of Excel 2021,IBM SPSS Modeler 18.0 and IBM SPSS Statistics 27.0 were used for frequency of use,medicinal properties,association rule analysis,and systematic clustering analysis and finally visualized by Cytoscape 3.7.2,RStudio.Results Through screening,a total of 179 compound patents met the inclusion criteria,involving 466 kinds of Chinese materia medica,and the top 5 high-frequency drugs were Pugongying,Huangbai,Gancao,Jinyinhua,Bianxu.The medicinal properties are mainly cold and mild;The medicinal taste is characterized by sweetness,bitterness,and bitterness;The main meridians of drugs are liver,lung and kidney meridians.Common couplet medicines included Qumai-Bianxu,Gancao-Bianxu and the three herb drug combinations included Cheqianzi-Qumai-Bianxu,Gancao-Qumai-Bianxu.A total of 5 high-frequency combinations of traditional Chinese medicine were obtained by cluster analysis.Conclusion This study preliminarily reveals the compatibility and medication rules of traditional Chinese medicine in the treatment of UTI,which provides data support for the optimization of clinical syndrome differentiation and treatment system and the development of new prescriptions.
