Clinical characteristics of premature rupture of membranes complicated with histological chorioamnionitis
10.3969/j.issn.1673-9701.2025.21.007
- VernacularTitle:胎膜早破并发组织学绒毛膜羊膜炎特征分析
- Author:
Mengshi YU
1
;
Qian MAO
;
Qingqing LUO
Author Information
1. 西南医科大学附属医院产科,四川泸州 646000
- Publication Type:Journal Article
- Keywords:
Histological chorioamnionitis;
Premature rupture of membranes;
Mother-child outcome
- From:
China Modern Doctor
2025;63(21):28-32
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical features of premature rupture of membrane(PROM)complicated with histologic chorioamnionitis(HCA),and to provide insights for clinical management of such pregnant women and their newborns.Methods A total of 202 cases of PROM pregnant women who gave birth and performed placental pathological examination in the Affiliated Hospital of Southwest Medical University from January to December 2021 were retrospectively analyzed.According to the histopathological results,the pregnant women were divided into HCA group(n=151)and control group(n=51),and the prenatal factors and short-term maternal-fetal pregnancy outcomes of two groups were compared and analyzed.Results The amniotic fluid contamination rate,white blood cell count,neutrophil count and serum amyloid A levels in HCA group were significantly higher than those in control group(P＜0.05).There was a higher incidence of early neonatal septicemia in HCA group than in control group(P＜0.05).Conclusion The risk of early-onset sepsis in neonates with PROM complicated with HCA significantly increases.It is necessary to strengthen the screening and early intervention in such cases.Amniotic fluid contamination and increased maternal infection indicators are associated with the occurrence of HCA,which may has potential value in predicting HCA occurrence.
