Clinical study on the treatment of chronic sinusitis in children by nasal irrigation with She Ethnic Medicine Melastoma dodecandrum
10.3969/j.issn.1673-9701.2025.20.011
- VernacularTitle:畲药地菍鼻腔冲洗治疗儿童慢性鼻窦炎临床研究
- Author:
Jun WU
1
;
Houxing LEI
;
Xiaoqin ZHANG
;
Yixing ZHANG
Author Information
1. 丽水市中医院儿科,浙江丽水 323000;丽水市畲药重点实验室,浙江丽水 323000
- Publication Type:Journal Article
- Keywords:
Melastoma dodecandrum;
Nasal irrigation;
Chronic sinusitis;
Clinical research
- From:
China Modern Doctor
2025;63(20):44-46
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of Melastoma dodecandrum(MD)nasal irrigation in the treatment of chronic sinusitis in children.Methods A total of 63 children with chronic sinusitis,treated at Lishui Hospital of Traditional Chinese Medicine from January to June 2022 were selected as the study subjects.They were divided into control group(n=33)and treatment group(n=30)by a random number table method.The control group received nasal irrigation with 2.3％ hypertonic saline,while the treatment group received nasal irrigation with MD.The clinical efficacy,Lund-Mackay score of sinus CT,levels of interleukin(IL)-6,IL-8,and tumor necrosis factor(TNF)-α in the nasal irrigation fluid,and safety were compared between two groups.Results After 3 months of treatment,the effective rate of treatment group was higher than that of control group(P＜0.05).After treatment,the CT Lund-Mackay scores for both groups of children decreased,with treatment group showing a better improvement(P＜0.05).Levels of IL-6,IL-8,and TNF-α in the nasal irrigation fluid of both groups were significantly reduced(P＜0.05).Conclusion MD nasal irrigation can effectively treat chronic sinusitis in children,the clinical total effective rate,IL-6,IL-8 inflammatory factors and sinus CT Lund-Mackay score improvement are better than 2.3％hypertonic physiological seawater,and safety is good.
