Study of safety and clinical outcomes of ommaya reservoir combined with external ventricular drainage for intraventricular hemorrhage
10.3969/j.issn.1673-9701.2025.20.007
- VernacularTitle:Ommaya囊联合脑室外引流治疗脑室积血的安全性及临床效果观察
- Author:
Bing QIU
1
;
Zhengyang LI
;
Xing ZHENG
;
Yuan HU
Author Information
1. 江西省宜春市人民医院神经外二科,江西宜春 336000
- Publication Type:Journal Article
- Keywords:
Ommaya reservoir;
External ventricular drainage;
Blood-brain barrier;
Intracranial infection
- From:
China Modern Doctor
2025;63(20):26-30
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate safety and clinical effect of Ommaya reservoir combined with external ventricular drainage for intraventricular hematoma(IVH),and to analyze the effects on neurological recovery,blood-brain-barrier(BBB)protection and the incidence of complications.Methods A total of 100 patients admitted to Yichun People's Hospital of Jiangxi Province for IVH and underwent surgical treatment from January 2021 to January 2023 were selected as the study subjects.Using a random number table,the patients were divided into control group(n=50)and treatment group(n=50).The treatment group received Ommaya reservoiv combined with external ventricular drainage,while the control group received conventional external ventricular drainage.The postoperative improvement rate,neurological recovery,BBB index,S100 calcium binding protein beta(neural)(S100β),myelin basic protein(MBP)levels,and hematoma clearance rate were compared between two groups.The incidence of complications in both groups was monitored over a 24-month follow-up period.Results At 3d,7d,and 14d post-surgery,the hematoma clearance rate in treatment group was higher than that in control group.At 3,12,and 24 months post-surgery,the patients of treatment group showed a higher improvement rate then that of control group,with better performance in National Institutes of Health stroke scale and Canadian stroke scale scores for neurological recovery,all differences being statistically significant(P＜0.05).During follow-ups at 1,3,12,and 24 months post-surgery,the BBB index,S100β,and MBP levels in treatment group were all lower than those in the control group,with all differences being statistically significant(P＜0.05).At 24 months post-surgery,the patients of treatment group had a lower incidence of complications than that of control group(P＜0.05).Conclusion Ommaya reservoir combined with exteral ventricular drainage can significantly improve neurological function,protect the BBB,and show good long-term efficacy in follow-up.
