Analysis of factors affecting colorectal serrated lesions combined with advanced neoplasia

VernacularTitle:结直肠锯齿状病变合并进展期肿瘤的影响因素分析
Author: Wentian ZHANG ¹ ; Linhua YAO ¹ ; Huifei LU ¹ ; Jing YU ¹
Author Information

1. 浙江省湖州市第一人民医院消化内科,浙江湖州 313000
Publication Type:Journal Article
Keywords: Serrated lesions; Adenoma; Advanced neoplasia; Risk factor
From: China Modern Doctor 2025;63(20):22-25
CountryChina
Language:Chinese
Abstract: Objective To investigate the incidence of colorectal serrated lesions(SL)combined with advanced neoplasia(AN)and to analyze the risk factors for SL combined AN.Methods A total of 297 patients with colorectal polyps detected by endoscopy and pathologically suggestive of SL from 1st October 2021 to 30th September 2023 in the First People's Hospital of Huzhou.They were divided into combined group(n=33)and uncomplicated group(n=264)according to whether they were combined with AN or not,and the clinicopathologic differences between two groups were compared and the coexisting risk factors were analyzed.Results Age ≥ 50 years,male,history of polyps,polyp size and different SL subtypes were all risk factors for SL combined with AN,and the difference was statistically significant(P＜0.05).Logistic regression analysis revealed that age,male,history of polypos,and SL size were independent risk factors for SL combined with AN.Conclusion Males,older age,previous history of polyps,and larger SL lesions were more likely to have combined AN.