Construction and analysis of a prediction model of hypertension with left ventricular diastolic dysfunction based on the random forest algorithm
10.3969/j.issn.1673-9701.2025.20.002
- VernacularTitle:基于随机森林算法的高血压合并左室舒张功能障碍预测模型的构建与分析
- Author:
Tingting WANG
1
;
Wei ZHOU
1
Author Information
1. 天津中医药大学第二附属医院心血管内科,天津 300143
- Publication Type:Journal Article
- Keywords:
Hypertension;
Left ventricular diastolic dysfunction;
Random forest algorithm
- From:
China Modern Doctor
2025;63(20):6-10
- CountryChina
- Language:Chinese
-
Abstract:
Objective To construct a random forest model for risk factor prediction and verification,and to explore the influencing factors of hypertension(EH)combined with left ventricular diastolic dysfunction(LVDD).Methods A total of 300 patients with EH who were hospitalized in the Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine from October 2023 to July 2024 were selected as the study subjects.The patients were divided into EH group(n=60)and LVDD group(n=240)by whether LVDD was combined,the general data and biochemical indexes of two groups were compared,and the influencing factors of EH combined with LVDD were analyzed by Logistic regression,and a random forest model was constructed.Results Compared with EH group,LVDD group had an increase in age,EH grade,EH risk stratification,course of disease,proportion of coronary heart disease,white blood cells(WBC),platelet(PLT),interleukin(IL)-6,total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),alkaline phosphatase(ALP),creatine kinase(CK),pro-brain natriuretic peptide(Pro-BNP),and high-density lipoprotein cholesterol and albumin(ALB)decreased(P＜0.05).Logistic regression analysis showed that EH grade,EH risk stratification,disease course,proportion of coronary heart disease,WBC,IL-6,TC,LDL-C,ALB,ALP,Pro-BNP were the influencing factors of EH and LVDD,and ALB was the protective factor.Conclusion IL-6,ALB,ALP,LDL-C,Pro-BNP,TC,EH grade,EH risk stratification,and WBC are the influencing factors of EH complicated with LVDD,which are helpful for early clinical prevention and treatment.
