Distribution of Clinical Features and Correlation Analysis between TCM Syndromes and Laboratory Indexes in 924 Cases of Atrial Fibrillation
10.19879/j.cnki.1005-5304.202412024
- VernacularTitle:924例心房颤动患者临床特征分布及中医证型与实验室指标相关性分析
- Author:
Ailin HOU
1
;
Yuxuan LIU
;
Hongbo HUANG
;
Ying ZHANG
;
Dazhuo SHI
Author Information
1. 北京中医药大学研究生院,北京 100029;中国中医科学院西苑医院,北京 100091
- Publication Type:Journal Article
- Keywords:
atrial fibrillation;
clinical features;
TCM syndromes;
correlation;
differentiation of disease,syndromes and body
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(8):153-158
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the distribution of clinical features and the correlation between TCM syndromes and laboratory indicators in patients with atrial fibrillation.Methods Retrospective analysis was performed on 924 patients with atrial fibrillation who were hospitalized in Xiyuan Hospital of China Academy of Chinese Medical Sciences from January 2016 to December 2023.The distribution pattern of TCM syndromes in patients with atrial fibrillation was analyzed,and the correlation between TCM syndromes and age,gender,past history,inflammatory indicators and biochemical indicators were explored.Results The study included 924 atrial fibrillation patients,predominantly female and mostly middle-aged or elderly.The main TCM syndrome types were qi-yin deficiency syndrome,qi deficiency and blood stasis syndrome,phlegm fire disturbance syndrome and phlegm blood stasis obstruction syndrome.Correlation analysis showed that patients with qi-yin deficiency syndrome had lower total protein and globulin,and the two were negatively correlated;qi deficiency and blood stasis syndrome were positively correlated with high density lipoprotein cholesterol levels;patients with phlegm fire disturbance syndrome were mostly male,younger in age and had a higher proportion of smoking history.They were negatively correlated with gender,age,and smoking history,and positively correlated with comorbidities of coronary heart disease,white blood cells,neutrophils,total protein,albumin,and globulin;patients with phlegm blood stasis obstruction syndrome were positively correlated with creatine kinase and uric acid,with statistical significance(P<0.05).Conclusion The TCM syndrome of atrial fibrillation is mainly characterized by qi-yin deficiency,and the proportion of phlegm and fire disturbance syndrome is increasing year by year.There is a correlation between the TCM syndromes of atrial fibrillation and clinical features(gender,age,past history),laboratory indicators such as inflammatory markers(WBC,NE,SII,NLR),total proteins,globulins,high density lipoprotein cholesterol,creatine kinase and uric acid,which can provide a guide to the"differentiation of disease,syndromes and body"in the diagnosis of atrial fibrillation.
