Predictive value of dNLR and NHHR for postoperative in-hospital outcomes in patients with acute myocardial infarction after PCI
10.3969/j.issn.1009-0126.2025.08.005
- VernacularTitle:两种比值对急性心肌梗死患者经皮冠状动脉介入治疗术后在院转归的预测价值
- Author:
Jianmei ZHENG
1
;
Gang WEI
1
;
Wei LI
1
Author Information
1. 646000 泸州,西南医科大学附属医院心血管内科
- Publication Type:Journal Article
- Keywords:
myocardial infarction;
prognosis;
neutropenia;
lymphocytes;
cholesterol,HDL
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(8):996-1000
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the predictive value of derived neutrophil lymphocyte ratio(dNLR)and non-high-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio(NHHR)for in-hospital outcomes of acute myocardial infarction(AMI)patients after PCI.Methods A total of 206 AMI patients undergoing PCI in our department from January 2021 to December 2023 were recruited,and according to their outcomes after PCI,they were divided into a good prognosis group(174 cases)and a poor prognosis group(32 cases).The clinical data were collected,and the dNLR and NHHR values were calculated.ROC curve was plotted to evaluate the predictive value of dNLR,NHHR and their combination for in-hospital outcomes of AMI pa-tients after PCI.Multivariate logistic regression analysis was applied to identify the influencing factors for in-hospital outcomes of AMI patients after PCI.Results The poor prognosis group had significantly higher Gensini score,larger proportions of NYHA Classes Ⅲ+Ⅳ and multi-vessel lesions,and elevated dNLR and NHHR,and lower LVEF value than the good prognosis group(P＜0.05,P＜0.01).The AUC value of dNLR,NHHR and their combination in predicting in-hospital outcomes of AMI patients after PCI was 0.758(95％CI:0.713-0.808),0.812(95％CI:0.767-0.857)and 0.914(95％CI:0.869-0.964),respectively.Multivariate logistic regression analysis showed that LVEF(OR=2.519,95％CI:1.249-5.082,P=0.010),multi-vessel lesions(OR=2.323,95％CI:1.358-3.975,P=0.002),dNLR(OR=3.031,95％CI:1.793-5.126,P=0.001),and NHHR(OR=3.480,95％CI:1.873-6.465,P=0.001)were influencing factors for in-hospital outcomes in AMI patients after PCI(P＜0.05).Conclusion High dNLR and NHHR values are closely associated with poor outcomes in AMI patients after PCI,and their combination may be an indicator to predict the outcomes after PCI.
