Sleep disorder and mental fatigue in elderly patients with cerebral small vessel disease
10.3969/j.issn.1009-0126.2025.08.018
- VernacularTitle:老年脑小血管病患者睡眠障碍及精神疲劳的研究
- Author:
Cunsheng WEI
1
;
Yingying XUE
;
Qian LI
;
Xiaorong YU
;
Meng CAO
;
Junying JIANG
;
Xuemei CHEN
Author Information
1. 211100 南京医科大学附属江宁医院南京市江宁医院神经内科
- Publication Type:Journal Article
- Keywords:
cerebral small vessel diseases;
sleep disorders;
mental fatigue;
global burden of disease
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(8):1061-1064
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the sleep quality and mental fatigue level in elderly patients with cerebrovascular small disease(CSVD).Methods A total of 222 patients aged over 65 years old hospitalized due to chronic diseases in Department of Neurology of the Affiliated Jiangning Hospi-tal of Nanjing Medical University from August 2022 to June 2024 were recruited prospectively and continuously.According to the CSVD score,they were divided into a CSVD group(CSVD score≥1,148 cases)and a non-CSVD group(CSVD score=0,74 cases).All the patients were evaluated by sleep quality,fatigue and neuropsychological scale when they were fully cooperated and in good condition.Subsequently,the patients in the CSVD group were further assigned into a good sleep subgroup(117 cases)and a poor sleep subgroup(31 patients).Results The CSVD group had significantly higher total score of Pittsburgh sleep quality index(PSQI),sleep quality score,sleep disturbance score,total score of self-rating fatigue,and mental fatigue score than the non-CSVD group(P＜0.01).The sleep quality score,sleep disturbance score,and mental fatigue score were risk factors for CSVD(P＜0.05).The mental fatigue score was significantly higher in the CSVD patients with poor sleep than those with good sleep(4.13±1.15 vs 2.50±1.92,P＜0.01).Conclusion Elderly CSVD patients were more likely to have decreased sleep quality and mental fatigue,and among them,those with poor sleep quality are prone to having mental fatigue than those with good sleep.
