The influence of intensified blood glucose control on the diaphragmatic function of patients with sepsis
10.3969/j.issn.1673-9701.2025.19.010
- VernacularTitle:强化血糖控制对脓毒症患者膈肌功能的影响
- Author:
Huishan WU
1
;
Weinan YING
;
Yinchao ZHOU
;
Zhouzhou DONG
Author Information
1. 宁波大学附属李惠利医院重症医学科,浙江宁波 315040
- Publication Type:Journal Article
- Keywords:
Intensified blood glucose control;
Sepsis;
Hyperglycemia;
Diaphragmatic function;
Ultrasound
- From:
China Modern Doctor
2025;63(19):46-50
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of intensified blood glucose control on the diaphragmatic function of patients with sepsis in the intensive care unit(ICU).Methods Sixty-six sepsis patients admitted to the ICU of Affiliated Lihuili Hospital of Ningbo University from January to December 2024 were selected and divided into experimental group and control group according to the random number table method,with 33 cases in each group.The experimental group received intensified blood glucose control,while control group received conventional blood glucose control.The diaphragm distance(DD)and diaphragm thickness fraction(DTF)of two groups of patients were continuously measured by bedside ultrasound,and the mechanical ventilation time,weaning outcome and hospital stay were recorded.Results With the prolongation of treatment time and mechanical ventilation time,the DD and DTF of both groups of patients showed an upward trend.There was no statistically significant difference in DD between two groups of patients at different times(P＞0.05).On the 4th and 6th days,the DTF of patients in experimental group was significantly greater than that in control group(P＜0.05).The weaning success rate of patients in experimental group was significantly higher than that in control group(P=0.026).There was no statistically significant difference in mechanical ventilation time,ICU stay time and total hospital stay time between two groups of patients(P＞0.05).There was no statistically significant difference in the incidence of hypoglycemia between two groups of patients(P＞0.05).Conclusion Intensified control of blood glucose can improve diaphragmatic function of patients with sepsis in the ICU,increase the success rate of weaning from the ventilator,and has high safety.
