Effect of Different Intraoperative Oxygen Concentrations on Early Postoperative Myocardial Injury in Patients With Coronary Heart Disease Undergoing Laparoscopic Surgery:a Prospective Randomized Controlled Study
10.3969/j.issn.1009-6604.2025.07.002
- VernacularTitle:术中不同水平氧浓度对冠心病患者腹腔镜手术后早期心肌损伤的影响:前瞻性随机对照研究
- Author:
Yuanzhao ZHUANG
1
;
Xinyi DAN
1
;
Jingyang ZENG
1
;
Changcheng JIANG
1
;
Jiaxiao SUN
1
Author Information
1. 福建医科大学附属泉州第一医院麻醉科,泉州 362000
- Publication Type:Journal Article
- Keywords:
Oxygen concentration;
Coronary heart disease;
Laparoscopic surgery;
Myocardial injury
- From:
Chinese Journal of Minimally Invasive Surgery
2025;25(7):393-397
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of different intraoperative oxygen concentrations on myocardial injury after noncardiac surgery(MINS)in patients with coronary heart disease undergoing laparoscopic surgery.Methods A total of 76 patients with coronary heart disease scheduled for laparoscopic surgery between January and December 2024 were randomly assigned to group L(FiO2=0.3,n=39)or group H(FiO2=0.8,n=37).In the group L,if intraoperative oxygen saturation fell below 92%,FiO2 was increased incrementally by0.03-0.1 as required.MINS was defined as postoperative high-sensitivity troponin T(hs-TnT)levels>65 ng/L,or 20 ng/L0.05).Conclusion Maintaining a lower intraoperative oxygen concentration(FiO2=0.3)in patients with coronary heart disease undergoing laparoscopic surgery reduces early postoperative myocardial injury markers and may help mitigate MINS.
